Research in the Buchwald Group combines elements of organic synthesis, physical organic chemistry and organometallic chemistry to devise catalytic processes of use in solving problems of fundamental importance.
The Ceyer group explores the atomic level dynamics of the interactions of molecules with surfaces of materials that serve as catalysts relevant to energy production and environmental sustainability or as templates for nanodevices.
The central focus of the Chakraborty Group is to understand the mechanistic underpinnings of the adaptive immune response to pathogens, and harness this understanding to help design better vaccines and therapies.
Current investigations in our laboratory focus on the development of new synthetic methods and strategies, and their application in the total synthesis of natural products and biologically important compounds.
By combining X-ray crystallography, cryo-electron microscopy and other biophysical methods, the goal of the Drennan lab is to “visualize” molecular processes by obtaining snapshots of enzymes in action.
The Gilliard Lab is engaged in energy-relevant chemical synthesis at the interface of inorganic and organic chemistry that impacts the discovery of new chemical reagents and the design of redox-active and/or luminescent molecular materials.
Employing a multidisciplinary approach involving synthesis, state-of-the-art spectroscopy, molecular modeling, enzymology, and molecular biology to address fundamental problems at the interface of chemistry and biology.
The mission of the Jamison group is to accelerate chemical synthesis through new reactions and technologies, particularly through the use of continuous flow synthesis, nickel-catalysis and epoxide-opening cascades.
Enzymatic catalysis in nonaqueous solvents, enzymes as stereoselective catalysts in organic synthesis, novel microbicidal materials, and the stabilization and delivery of macromolecular pharmaceuticals.
The Kulik group leverages multi-scale modeling, electronic structure calculations, and machine learning for the discovery of new molecules and mechanisms in a range of materials from metal-organic frameworks to enzymes and organometallics.
The focus of Professor Lippard's research is on the synthesis, reactions, physical and structural properties of metal complexes as models for the active sites of metalloproteins and as anti-cancer drugs.
Research in the McGuire Group uses the tools of physical chemistry, molecular spectroscopy, and observational astrophysics to understand how the chemical ingredients for life evolve with and help shape the formation of stars and planets.
The Peng Laboratory develops optical imaging techniques and nanoprobes to enable long-term single-molecule imaging in living systems and reveal molecular interactions that are responsible for human diseases.
The Pentelute Lab develops new protein modification chemistries, adapts nature's machines for efficient macromolecule delivery into cells, invents flow technologies for rapid biopolymer production, and discovers peptide binders to proteins.
Using techniques that range from synthetic chemistry to cell biology, the Raines group is illuminating in atomic detail both the chemical basis and the biological purpose for protein structure and protein function.
Professor Steinfeld's research interests evolved from focusing on obtaining kinetic data for physical and chemical systems using time-resolved spectroscopy, to ultimately studying gigaseconds and large, interconnected systems.
Our main objective is to understand the molecular chemistry that underlies global biogeochemical cycles, with the ultimate goal of deploying this knowledge to improve human health and positively impact the environment.
Broadly focused on synthetic, supramolecular, analytical, and materials chemistry, the Swager Group is interested in a spectrum of topics with an emphasis on the synthesis and construction of functional assemblies.
The Zhang Lab aims to build a global framework of the human genome that connects its sequence with structure and activity, and to enable quantitative and predictive modeling of genome structure and function.