Research in the Buchwald Group combines elements of organic synthesis, physical organic chemistry and organometallic chemistry to devise catalytic processes of use in solving problems of fundamental importance.
Current investigations in our laboratory focus on the development of new synthetic methods and strategies, and their application in the total synthesis of natural products and biologically important compounds.
The Gilliard Lab is engaged in energy-relevant chemical synthesis at the interface of inorganic and organic chemistry that impacts the discovery of new chemical reagents and the design of redox-active and/or luminescent molecular materials.
The Johnson Laboratory uses chemical and biophysical tools to understand and tune the activity of molecular chaperone proteins in protein misfolding diseases.
The Pentelute Lab develops new protein modification chemistries, adapts nature's machines for efficient macromolecule delivery into cells, invents flow technologies for rapid biopolymer production, and discovers peptide binders to proteins.
Research in the Radosevich group centers on the invention of new homogeneous catalysts and reagents based on inexpensive and earth-abundant elements of the p-block.
Using techniques that range from synthetic chemistry to cell biology, the Raines group is illuminating in atomic detail both the chemical basis and the biological purpose for protein structure and protein function.
The Shoulders Laboratory (1) studies how cells fold proteins and (2) develops and applies next-generation protein engineering and directed evolution techniques to address biotechnology challenges.
Broadly focused on synthetic, supramolecular, analytical, and materials chemistry, the Swager Group is interested in a spectrum of topics with an emphasis on the synthesis and construction of functional assemblies.
Research in the Wendlandt Group focuses on the development of selective, catalytic reactions using the tools of organic/organometallic synthesis and physical organic chemistry.