MIT Chemistry Directory

Alexander K Shalek

Assistant Professor

Research in the Shalek group will be directed towards the development and application of new technologies that will facilitate the understanding of how cells collectively perform systems-level functions in healthy and diseased states. With respect to technology development, the group will leverage recent advances in nanotechnology and chemical biology to establish a host of core, cross-disciplinary platforms that will collectively enable them to extensively profile and precisely control cells and their interactions within the context of complex systems. With respect to biological applications, the group will focus on how cellular heterogeneity and cell-to-cell communication drive ensemble-level decision-making in the immune system, with an emphasis on “two-body” interaction (e.g., host cell-virus interactions, innate immune control of adaptive immunity, tumor infiltration by immune cells). The goal is to not only provide broadly applicable experimental tools but also help transform the way in which we think about single cells, cell-cell interactions, diseased cellular states and therapeutics so as to create a new paradigm for understanding and designing systems-level cellular behaviors in multicellular organisms.

Contact Information

t: 6173245670
e: SHALEK@MIT.EDU

Office

E25-348A

Education

B.A. 2004, COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
M.A. 2006, HARVARD UNIVERSITY
Ph.D. 2011, HARVARD UNIVERSITY

Administrative Assistant

Michelle Morrison

Email: mmori35@mit.edu
Tel: (617) 715-2247

Room  E25-335
77 Massachusetts Ave.
Cambridge, MA 02139