Dr. Alex Shalek to Join the Department

May 29, 2014

Dr. Alex Shalek will be joining the department as an assistant professor on July 1, 2014.

Research in the Shalek group will be directed towards the development and application of new technologies that will facilitate the understanding of how cells collectively perform systems-level functions in healthy and diseased states. With respect to technology development, the group will leverage recent advances in nanotechnology and chemical biology to establish a host of core, cross-disciplinary platforms that will collectively enable them to extensively profile and precisely control cells and their interactions within the context of complex systems. With respect to biological applications, the group will focus on how cellular heterogeneity and cell-to-cell communication drive ensemble-level decision-making in the immune system, with an emphasis on “two-body” interaction (e.g., host cell-virus interactions, innate immune control of adaptive immunity, tumor infiltration by immune cells). The goal is to not only provide broadly applicable experimental tools but also help transform the way in which we think about single cells, cell-cell interactions, diseased cellular states and therapeutics so as to create a new paradigm for understanding and designing systems-level cellular behaviors in multicellular organisms.